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I can only speak from my experience in the 54th games, and I enjoyed being part of one of the larger (if not the largest?) alliances. Then again, it was with people I enjoyed role playing with, interesting characters... it was really fun. But it seems like betrayals have become very common here, and well, that's never fun for the character being betrayed (obviously), so maybe a smaller alliance would be safer. Of course the loner path ensures that you won't get your head smashed in the middle of the night, but fights with any of the larger groups basically guarantees that the loner will die.

That being said, I also think it's just more interesting to have your character in an alliance. There's lots of development to be had when you're going it alone, but seeing as this is a role play site, we naturally want our characters to have lots of interactions, besides the fights, you know? Even if your character doesn't trust easily, it's more interesting to have them in an alliance where they are totally paranoid because of the constant suspicion if their fellow allies, rather than to essentially role play with yourself.